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I've been trying to breed some heterozygous mice for some gene-dosage experiments, and one of the two breeding cages I set up finally produced a litter of mouse pups. Here is an iPhone video of the cage, something like 5 days old. Hopefully all except one or two will survive and I can do some work. I'll wean these mice in a few weeks. If I still owned snakes and I were unscrupulous I'd take a few of these home with me for pet food.






I don't make many videos anymore, I suppose I should get back to doing that from time to time. I have been told I have wonderful use of the Z-axis, which is something I think a man can only hear a few times in his life without it impelling him through the cinematographic glass ceiling.

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( 4 comments — Leave a comment )
skorzy
Jan. 12th, 2010 10:47 pm (UTC)
Although I didn't work in the vivarium at UMASS Medical, I did have some mouse populations that were part of my project. I remember way back when we developed the JNK3 homozygous knock-out mice and how we discovered the hippocampal dysfunction. A loud clap, or sharp rap on the table near the mice stressed them enough to cause unregulated hippocampal apoptosis. The result were mice that had seizures as a result of slapping the table near them.

Biology is awesome.
just_the_ash
Jan. 13th, 2010 04:47 pm (UTC)
You duplicated the effects of finals week in mice?! Awesome! :D
just_the_ash
Jan. 13th, 2010 04:46 pm (UTC)
Those are some darn Gothy-lookin' mice there, sir. All they'd need would be ear tags to complete the look.
floyd_mephit
Jan. 13th, 2010 06:21 pm (UTC)
Actually in many labs mice are labelled via ear-punch, with chirality and number used for differentiation of sex and genotype, but our lab is post-punk I guess so we just use stickers on the cages.
( 4 comments — Leave a comment )